Booting our Raspberry Pi 4 from USB is already possible, with any SSD or Pendrive hard drive, if you follow this mini tutorial to the letter
Raspberry Pi Mount a USB Drive Tutorial - Pi My Life Up
Raspberry Pi Cheap SSD Upgrade Guide - James A. Chambers
Upgrade your Raspberry Pi 4 with a NVMe boot drive
Three Different Ways to Boot a Raspberry Pi From a USB Drive
How to build a Raspberry Pi NAS - Raspberry Pi
The X820 V3.0 Version SATA HDD/SSD storage expansion board provides an complete storage solution for your Raspberry Pi.It only support 2.5 inch SATA
Raspberry Pi 3B+/3B X820 V3.0 USB 3.0 2.5
Plex on a Raspberry Pi 4 is a mixed experience - Computer Crap
Raspberry Pi: How to boot from USB, SSD or network - PC Guide
How To Connect a Drive (HDD/SSD) to a Raspberry Pi